When transplant specialists place a retrieved donor organ in the heart-in-a-box machine, it perfuses the organ with warm, oxygenated blood, reviving the heart from nonbeating to beating status. In addition, the heart-in-a-box has the potential to widen the donor pool by supporting the novel use of donation after circulatory death (DCD) hearts by reviving and supporting the recovery of nonbeating hearts. However, the new system preserves a heart while it is beating, extending the time between retrieval and transplant by several hours. The standard heart preservation technique preserves a heart for a window of approximately 3 to 5 hours. New perfusion system preserves a heart while it is beating, extending the time between retrieval and transplant by several hours.
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